Understanding the Diagnostic Importance and Clinical Significance of tTG and DGP Antibodies in Celiac Disease
Introduction Celiac disease is a chronic autoimmune disorder triggered by the ingestion of gluten in genetically predisposed individuals. Early diagnosis is critical to prevent complications such as malabsorption, osteoporosis, infertility, and intestinal lymphoma. Among the tools available for diagnosis, serological testing for specific antibodies—namely, tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP)—plays a pivotal role….